BDBM42528 (E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-one::(E)-3-(1-naphthyl)-1-(4-pyridyl)prop-2-en-1-one::(E)-3-naphthalen-1-yl-1-pyridin-4-yl-prop-2-en-1-one::(E)-3-naphthalen-1-yl-1-pyridin-4-ylprop-2-en-1-one::3-(1-naphthyl)-1-(4-pyridinyl)-2-propen-1-one::MLS000573147::SMR000185081::cid_5338258

SMILES O=C(\C=C\c1cccc2ccccc12)c1ccncc1

InChI Key InChIKey=GCRUQDILILGFIY-CMDGGOBGSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42528   

TargetCytochrome P450 3A4(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM42528((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in HEK293 cells using dibenzylfluorescein as substrate pretreated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM42528((E)-3-(1-naphthalenyl)-1-pyridin-4-yl-2-propen-1-o...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human CYP3A4 expressed in yeast microsomal membranes using dibenzylfluorescein as substrate measured after 10 mins by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed